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Anti-CD138 antibody [ZR251] (STJ180555)

Formalin-fixed, paraffin-embedded human tonsil stained with anti-CD138 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of plasma cells and squamous epithelium

Anti-CD138 antibody [ZR251] (STJ180555)

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STJ180555

£158.50 - £560.50

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General Information
Product Properties
Target Information
Additional Info
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Host:	Rabbit
Applications:	IHC-P
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-CD138 is suitable for use in Immunohistochemistry research applications.

Clonality:	Monoclonal
Clone ID:	ZR251
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification:	Affinity purified
Dilution Range:	1:100-200
Storage Instruction:	Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.

Gene Symbol:	SDC1
Gene ID:	6382
Uniprot ID:	SDC1_HUMAN
Specificity:	Positive Control: Tonsil
Immunogen:	Recombinant fragment (around aa1-250) of human CD138 protein (exact sequence is proprietary)

Tissue Specificity	Detected in placenta (at protein level). Detected in fibroblasts (at protein level).
Post Translational Modifications	Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
Function	Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway.
Protein Name	Syndecan-1 Synd1 Cd Antigen Cd138
Database Links	Reactome: R-HSA-1971475 Reactome: R-HSA-2022928 Reactome: R-HSA-2024096 Reactome: R-HSA-202733 Reactome: R-HSA-3000170 Reactome: R-HSA-3560783 Reactome: R-HSA-3560801 Reactome: R-HSA-3656237 Reactome: R-HSA-3656253 Reactome: R-HSA-4420332 Reactome: R-HSA-449836 Reactome: R-HSA-9694614 Reactome: R-HSA-975634
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein Secreted Extracellular Exosome Shedding Of The Ectodomain Produces A Soluble Form
Alternative Antibody Names	Anti-Syndecan-1 antibody Anti-Synd1 antibody Anti-Cd Antigen Cd138 antibody Anti-SDC1 antibody Anti-SDC antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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