• Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:100
  • Western blot analysis of 293 cells using CD138 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-SDC1 antibody (191-240 aa) (STJ97305)

SKU:
STJ97305

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Syndecan-1 (191-240 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SDC1
Gene ID: 6382
Uniprot ID: SDC1_HUMAN
Immunogen Region: 191-240 aa
Specificity: CD138 Polyclonal Antibody detects endogenous levels of CD138 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human SDC1 at the amino acid range 191-240
Post Translational Modifications Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
Function Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway.
Protein Name Syndecan-1
Synd1
Cd Antigen Cd138
Database Links Reactome: R-HSA-1971475
Reactome: R-HSA-2022928
Reactome: R-HSA-2024096
Reactome: R-HSA-202733
Reactome: R-HSA-3000170
Reactome: R-HSA-3560783
Reactome: R-HSA-3560801
Reactome: R-HSA-3656237
Reactome: R-HSA-3656253
Reactome: R-HSA-4420332
Reactome: R-HSA-449836
Reactome: R-HSA-9694614
Reactome: R-HSA-975634
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Secreted
Extracellular Exosome
Shedding Of The Ectodomain Produces A Soluble Form
Alternative Antibody Names Anti-Syndecan-1 antibody
Anti-Synd1 antibody
Anti-Cd Antigen Cd138 antibody
Anti-SDC1 antibody
Anti-SDC antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance