Anti-CCT8 antibody [R07-4Y-4] (STJA0033106)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenPeptide
General Information
| Short Description | Mouse monoclonal anti-CCT8 for use in WB, IHC-P, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R07-4Y-4 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Purification | Protein G |
| Dilution Range | WB 1:500-1:1000IHC-P 1:50-1:100ICC:IF 1:50 |
| Formulation | Liquid in PBS, Glycerol and BSA |
| Storage Instruction | Store at-20°C. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CCT8 |
| Gene ID | 10694 |
| Uniprot ID | TCPQ_HUMAN |
| Immunogen | Peptide |
Additional Info
| Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. |
| Protein Name | T-Complex Protein 1 Subunit ThetaTcp-1-ThetaCct-ThetaChaperonin Containing T-Complex Polypeptide 1 Subunit 8Renal Carcinoma Antigen Ny-Ren-15 |
| Database Links | Reactome: R-HSA-389957Reactome: R-HSA-389960Reactome: R-HSA-390450Reactome: R-HSA-390471Reactome: R-HSA-5620922Reactome: R-HSA-6798695Reactome: R-HSA-6814122 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCilium Basal Body |
| Alternative Antibody Names | Anti-T-Complex Protein 1 Subunit Theta antibodyAnti-Tcp-1-Theta antibodyAnti-Cct-Theta antibodyAnti-Chaperonin Containing T-Complex Polypeptide 1 Subunit 8 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-15 antibodyAnti-CCT8 antibodyAnti-C21orf112 antibodyAnti-CCTQ antibodyAnti-KIAA0002 antibody |
Information sourced from Uniprot.org