Anti-CCT5 antibody (1-270) (STJ28632)

Name: Anti-CCT5 antibody (1-270) (STJ28632)
SKU: STJ28632
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ28632

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Short Description	Rabbit polyclonal CCT5 (1-270) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	CCT5
Gene ID	22948
Uniprot ID	TCPE_HUMAN
Immunogen Region	1-270
Immunogen Sequence	MASMGTLAFDEYGRPFLIIK DQDRKSRLMGLEALKSHIMA AKAVANTMRTSLGPNGLDKM MVDKDGDVTVTNDGATILSM MDVDHQIAKLMVELSKSQDD EIGDGTTGVVVLAGALLEEA EQLLDRGIHPIRIADGYEQA ARVAIEHLDKISDSVLVDIK DTEPLIQTAKTTLGSKVVNS CHRQMAEIAVNAVLTVADME RRDVDFELIKVEGKVGGRLE DTKLIKGVIVDKDFSHPQM
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CCT5 (NP_036205.1).

Post Translational Modifications	Ubiquitinated by the DCX(DCAF12) complex specifically recognizes the diglutamate (Glu-Glu) at the C-terminus, leading to its degradation.
Function	Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.
Protein Name	T-Complex Protein 1 Subunit Epsilon Tcp-1-Epsilon Cct-Epsilon Chaperonin Containing T-Complex Polypeptide 1 Subunit 5
Database Links	Reactome: R-HSA-389957 Reactome: R-HSA-389960 Reactome: R-HSA-390450 Reactome: R-HSA-390471 Reactome: R-HSA-5620922 Reactome: R-HSA-6814122
Cellular Localisation	Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome
Alternative Antibody Names	Anti-T-Complex Protein 1 Subunit Epsilon antibody Anti-Tcp-1-Epsilon antibody Anti-Cct-Epsilon antibody Anti-Chaperonin Containing T-Complex Polypeptide 1 Subunit 5 antibody Anti-CCT5 antibody Anti-CCTE antibody Anti-KIAA0098 antibody

Information sourced from Uniprot.org