| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CCT5 (1-270) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CCT5 |
| Gene ID: |
22948 |
| Uniprot ID: |
TCPE_HUMAN |
| Immunogen Region: |
1-270 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CCT5 (NP_036205.1). |
| Immunogen Sequence: |
MASMGTLAFDEYGRPFLIIK DQDRKSRLMGLEALKSHIMA AKAVANTMRTSLGPNGLDKM MVDKDGDVTVTNDGATILSM MDVDHQIAKLMVELSKSQDD EIGDGTTGVVVLAGALLEEA EQLLDRGIHPIRIADGYEQA ARVAIEHLDKISDSVLVDIK DTEPLIQTAKTTLGSKVVNS CHRQMAEIAVNAVLTVADME RRDVDFELIKVEGKVGGRLE DTKLIKGVIVDKDFSHPQM |
| Post Translational Modifications | Ubiquitinated by the DCX(DCAF12) complex specifically recognizes the diglutamate (Glu-Glu) at the C-terminus, leading to its degradation. |
| Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable). |
| Protein Name | T-Complex Protein 1 Subunit EpsilonTcp-1-EpsilonCct-Epsilon |
| Database Links | Reactome: R-HSA-389957Reactome: R-HSA-389960Reactome: R-HSA-390450Reactome: R-HSA-390471Reactome: R-HSA-5620922Reactome: R-HSA-6814122 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Antibody Names | Anti-T-Complex Protein 1 Subunit Epsilon antibodyAnti-Tcp-1-Epsilon antibodyAnti-Cct-Epsilon antibodyAnti-CCT5 antibodyAnti-CCTE antibodyAnti-KIAA0098 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
