• Immunohistochemistry analysis of CCR3 in paraffin-embedded mouse spleen using CCR3 Rabbit polyclonal antibody (STJ11103242) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of CCR3 in paraffin-embedded rat spleen using CCR3 Rabbit polyclonal antibody (STJ11103242) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using CCR3 Rabbit polyclonal antibody (STJ11103242) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-CCR3 antibody (146-226) (STJ11103242)

SKU:
STJ11103242

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CCR3 (146-226) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCR3
Gene ID: 1232
Uniprot ID: CCR3_HUMAN
Immunogen Region: 146-226
Immunogen: Recombinant fusion protein containing a sequence within amino acids 146-226 of human CCR3 (NP_001828.1).
Immunogen Sequence: TVTFGVITSIVTWGLAVLAA LPEFIFYETEELFEETLCSA LYPEDTVYSWRHFHTLRMTI FCLVLPLLVMAICYTGIIKT L
Tissue Specificity In eosinophils as well as trace amounts in neutrophils and monocytes.
Function Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.
Protein Name C-C Chemokine Receptor Type 3
C C Ckr3
C-C Ckr-3
Cc-Ckr-3
Ccr-3
Ccr3
Ckr 3
Ckr3
Eosinophil Eotaxin Receptor
Cd Antigen Cd193
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-C-C Chemokine Receptor Type 3 antibody
Anti-C C Ckr3 antibody
Anti-C-C Ckr-3 antibody
Anti-Cc-Ckr-3 antibody
Anti-Ccr-3 antibody
Anti-Ccr3 antibody
Anti-Ckr 3 antibody
Anti-Ckr3 antibody
Anti-Eosinophil Eotaxin Receptor antibody
Anti-Cd Antigen Cd193 antibody
Anti-CCR3 antibody
Anti-CMKBR3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance