Anti-CCR3 antibody (1-50) {Biotin} (STJ500403)

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STJ500403-100
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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-CCR3 (1-50) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Biotin
Isotype: IgG
Formulation: Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Purification: Affinity Purified
Concentration: 0.60-0.70 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: CCR3
Gene ID: 1232
Uniprot ID: CCR3_HUMAN
Immunogen Region: 1-50
Immunogen: Synthetic peptide taken within amino acid region 1-50 on human CCR3 protein.
Tissue Specificity In eosinophils as well as trace amounts in neutrophils and monocytes.
Function Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.
Protein Name C-C Chemokine Receptor Type 3
C C Ckr3
C-C Ckr-3
Cc-Ckr-3
Ccr-3
Ccr3
Ckr 3
Ckr3
Eosinophil Eotaxin Receptor
Cd Antigen Cd193
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-C-C Chemokine Receptor Type 3 antibody
Anti-C C Ckr3 antibody
Anti-C-C Ckr-3 antibody
Anti-Cc-Ckr-3 antibody
Anti-Ccr-3 antibody
Anti-Ccr3 antibody
Anti-Ckr 3 antibody
Anti-Ckr3 antibody
Anti-Eosinophil Eotaxin Receptor antibody
Anti-Cd Antigen Cd193 antibody
Anti-CCR3 antibody
Anti-CMKBR3 antibody

Information sourced from Uniprot.org

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