||Rabbit polyclonal anti-CCNY antibody is suitable for use in Western Blot and ELISA.
||FOR RESEARCH USE ONLY (RUO).
||Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
||CCNY antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
||Store at-20°C, and avoid repeat freeze-thaw cycles.
||WB 1:500-2000ELISA 1:5000-20000
||CCNY polyclonal antibody detects endogenous levels of protein.
||Synthesized peptide derived from human CCNY protein.
| Post Translational Modifications || Ubiquitinated.leading to its degradation. Heavily phosphorylated. Phosphorylation at Ser-71 and Ser-73 by CDK14 is enhanced during the G2 and M cell cycle phases, and creates a phosphodegron triggering SCF-dependent ubiquitination. |
| Function || Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription. |
| Protein Name || Cyclin-YCyc-YCyclin Box Protein 1Cyclin Fold Protein 1Cyclin-X |
| Cellular Localisation || Cell MembraneLipid-AnchorCytoplasmic SideIsoform 3: Nucleus |
| Alternative Antibody Names || Anti-Cyclin-Y antibodyAnti-Cyc-Y antibodyAnti-Cyclin Box Protein 1 antibodyAnti-Cyclin Fold Protein 1 antibodyAnti-Cyclin-X antibodyAnti-CCNY antibodyAnti-C10orf9 antibodyAnti-CBCP1 antibodyAnti-CFP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance