• Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Western blot analysis of lysates from Jurkat and COLO cells, using CCNB1IP1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using HEI10 Polyclonal Antibody diluted at 1：2000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-CCNB1IP1 antibody (201-250 aa) (STJ93487)

SKU:
STJ93487

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase CCNB1IP1 (201-250 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCNB1IP1
Gene ID: 57820
Uniprot ID: CIP1_HUMAN
Immunogen Region: 201-250 aa
Specificity: HEI10 Polyclonal Antibody detects endogenous levels of HEI10 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CCNB1IP1 at the amino acid range 201-250
Post Translational Modifications Ubiquitinated.autoubiquitinated. Phosphorylated by CDK1 on serine or threonine residues (in vitro).
Function Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over. Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis. E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.
Protein Name E3 Ubiquitin-Protein Ligase Ccnb1ip1
Cyclin-B1-Interacting Protein 1
Human Enhancer Of Invasion 10
Ring-Type E3 Ubiquitin Transferase Ccnb1ip1
Cellular Localisation Nucleus
Chromosome
Associates To The Synaptonemal Complex
Alternative Antibody Names Anti-E3 Ubiquitin-Protein Ligase Ccnb1ip1 antibody
Anti-Cyclin-B1-Interacting Protein 1 antibody
Anti-Human Enhancer Of Invasion 10 antibody
Anti-Ring-Type E3 Ubiquitin Transferase Ccnb1ip1 antibody
Anti-CCNB1IP1 antibody
Anti-C14orf18 antibody
Anti-HEI10 antibody

Information sourced from Uniprot.org

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