| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C-C motif chemokine 23 (40-120 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CCL23 |
| Gene ID: |
6368 |
| Uniprot ID: |
CCL23_HUMAN |
| Immunogen Region: |
40-120 aa |
| Specificity: |
CCL23 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 40-120 |
| Post Translational Modifications | The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms, CCL23(19-99), CCL23(22-99), CCL23(27-99) and CCL23(30-99) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro. |
| Function | Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23. |
| Protein Name | C-C Motif Chemokine 23Ck-Beta-8Ckb-8Macrophage Inflammatory Protein 3Mip-3Myeloid Progenitor Inhibitory Factor 1Mpif-1Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99 |
| Database Links | Reactome: R-HSA-416476 P55773-2Reactome: R-HSA-418594 P55773-2Reactome: R-HSA-444473 P55773-2 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 23 antibodyAnti-Ck-Beta-8 antibodyAnti-Ckb-8 antibodyAnti-Macrophage Inflammatory Protein 3 antibodyAnti-Mip-3 antibodyAnti-Myeloid Progenitor Inhibitory Factor 1 antibodyAnti-Mpif-1 antibodyAnti-Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99 antibodyAnti-CCL23 antibodyAnti-MIP3 antibodyAnti-MPIF1 antibodyAnti-SCYA23 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
