Host: |
Rabbit |
Applications: |
IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-C-C motif chemokine 19 (20-100 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CCL19 |
Gene ID: |
6363 |
Uniprot ID: |
CCL19_HUMAN |
Immunogen Region: |
20-100 aa |
Specificity: |
MIP-3 Beta Polyclonal Antibody detects endogenous levels of MIP-3 Beta protein. |
Immunogen: |
Synthesized peptide derived from MIP-3 Beta at the amino acid range 20-100 |
Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
Protein Name | C-C Motif Chemokine 19Beta-Chemokine Exodus-3Ck Beta-11Epstein-Barr Virus-Induced Molecule 1 Ligand ChemokineEbi1 Ligand ChemokineElcMacrophage Inflammatory Protein 3 BetaMip-3-BetaSmall-Inducible Cytokine A19 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-C-C Motif Chemokine 19 antibodyAnti-Beta-Chemokine Exodus-3 antibodyAnti-Ck Beta-11 antibodyAnti-Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine antibodyAnti-Ebi1 Ligand Chemokine antibodyAnti-Elc antibodyAnti-Macrophage Inflammatory Protein 3 Beta antibodyAnti-Mip-3-Beta antibodyAnti-Small-Inducible Cytokine A19 antibodyAnti-CCL19 antibodyAnti-ELC antibodyAnti-MIP3B antibodyAnti-SCYA19 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance