| Host: |
Rabbit |
| Applications: |
IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C-C motif chemokine 15 (51-100 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CCL15 |
| Gene ID: |
6359 |
| Uniprot ID: |
CCL15_HUMAN |
| Immunogen Region: |
51-100 aa |
| Specificity: |
The antibody detects endogenous MIP-5 |
| Immunogen: |
Synthetic peptide from the human protein at the amino acid range 51-100 |
| Post Translational Modifications | The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms CCL15(22-92), CCL15(25-92) and CCL15(29-92) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro. |
| Function | Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the CCL15. |
| Protein Name | C-C Motif Chemokine 15Chemokine Cc-2Hcc-2Leukotactin-1Lkn-1Mip-1 DeltaMacrophage Inflammatory Protein 5Mip-5Mrp-2bNcc-3Small-Inducible Cytokine A15 Cleaved Into - Ccl15(22-92 - Ccl15(25-92 - Ccl15(29-92 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 15 antibodyAnti-Chemokine Cc-2 antibodyAnti-Hcc-2 antibodyAnti-Leukotactin-1 antibodyAnti-Lkn-1 antibodyAnti-Mip-1 Delta antibodyAnti-Macrophage Inflammatory Protein 5 antibodyAnti-Mip-5 antibodyAnti-Mrp-2b antibodyAnti-Ncc-3 antibodyAnti-Small-Inducible Cytokine A15 Cleaved Into - Ccl15(22-92 - Ccl15(25-92 - Ccl15(29-92 antibodyAnti-CCL15 antibodyAnti-MIP5 antibodyAnti-NCC3 antibodyAnti-SCYA15 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
