Anti-CCK antibody (46-95 aa) (STJ92071)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CCK at the amino acid range 46-95
General Information
| Short Description | Rabbit polyclonal anti-Cholecystokinin (46-95 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCK |
| Gene ID | 885 |
| Uniprot ID | CCKN_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CCK at the amino acid range 46-95 |
| Immunogen Region | 46-95 aa |
| Specificity | CCK Polyclonal Antibody detects endogenous levels of CCK protein. |
Additional Info
| Post Translational Modifications | The precursor is cleaved by proteases to produce a number of active cholecystokinins. Cholecystokinin-5: The precursor is cleaved by ACE, which removes the Gly-Arg-Arg peptide at the C-terminus, leading to mature hormone. |
| Function | This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. |
| Protein Name | CholecystokininCck Cleaved Into - Cholecystokinin-58Cck58 - Cholecystokinin-58 Desnonopeptide(1-49-Cck58 - Cholecystokinin-39Cck39 - Cholecystokinin-33Cck33 - Cholecystokinin-25Cck25 - Cholecystokinin-18Cck18 - Cholecystokinin-12Cck12 - Cholecystokinin-8Cck8 - Cholecystokinin-7Cck7 - Cholecystokinin-5Cck5 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cholecystokinin antibodyAnti-Cck Cleaved Into - Cholecystokinin-58 antibodyAnti-Cck58 - Cholecystokinin-58 Desnonopeptide antibodyAnti-(1-49-Cck58 - Cholecystokinin-39 antibodyAnti-Cck39 - Cholecystokinin-33 antibodyAnti-Cck33 - Cholecystokinin-25 antibodyAnti-Cck25 - Cholecystokinin-18 antibodyAnti-Cck18 - Cholecystokinin-12 antibodyAnti-Cck12 - Cholecystokinin-8 antibodyAnti-Cck8 - Cholecystokinin-7 antibodyAnti-Cck7 - Cholecystokinin-5 antibodyAnti-Cck5 antibodyAnti-CCK antibody |
Information sourced from Uniprot.org