Host: | Goat |
Applications: | Pep-ELISA/WB/IHC |
Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-CCDC3 (134-148) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: In transfected HEK293 transiently expressing Human CCDC3 (DYKDDDDK tagged) , a band of approx. 36kDa is observed. No bands are observed in mock-transfected HEK293 and the same band is |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | CCDC3 |
Gene ID: | 83643 |
Uniprot ID: | CCDC3_HUMAN |
Immunogen Region: | 134-148 |
Accession Number: | NP_113643.1 |
Immunogen Sequence: | PHGVNFQDAIFPDTQ |
Function | Negatively regulates TNF-alpha-induced pro-inflammatory response in endothelial cells (ECs) via inhibition of TNF-alpha-induced NF-kappaB activation in ECs. Positively regulates lipid accumulation in adipose cells. |
Protein Name | Coiled-Coil Domain-Containing Protein 3Fat/Vessel-Derived Secretory ProteinFavine |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Coiled-Coil Domain-Containing Protein 3 antibodyAnti-Fat/Vessel-Derived Secretory Protein antibodyAnti-Favine antibodyAnti-CCDC3 antibody |
Information sourced from Uniprot.org