• Western blot analysis of extracts of U-87MG cells, using Caspr11 Rabbit monoclonal antibody (STJ11103532) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.

Anti-Caspr1 antibody (700-800) [S2MR] (STJ11103532)

SKU:
STJ11103532

£146.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Caspr1 (700-800) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S2MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CNTNAP1
Gene ID: 8506
Uniprot ID: CNTP1_HUMAN
Immunogen Region: 700-800
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700-800 of human Caspr11 (P78357).
Immunogen Sequence: EQHFYWGGSQPGIQRCACGL DRSCVDPALYCNCDADQPQW RTDKGLLTFVDHLPVTQVVI GDTNRSTSEAQFFLRPLRCY GDRNSWNTISFHTGAALRFP P
Tissue Specificity Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis.
Function Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells.
Protein Name Contactin-Associated Protein 1
Caspr
Caspr1
Neurexin Iv
Neurexin-4
P190
Database Links Reactome: R-HSA-447043
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Paranodal Septate Junction
Alternative Antibody Names Anti-Contactin-Associated Protein 1 antibody
Anti-Caspr antibody
Anti-Caspr1 antibody
Anti-Neurexin Iv antibody
Anti-Neurexin-4 antibody
Anti-P190 antibody
Anti-CNTNAP1 antibody
Anti-CASPR antibody
Anti-NRXN4 antibody

Information sourced from Uniprot.org

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