• Western blot analysis of various lysates using CARD19 Rabbit polyclonal antibody (STJ115162) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-CARD19 antibody (1-100) (STJ115162)

SKU:
STJ115162

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CARD19 (1-100) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CARD19
Gene ID: 84270
Uniprot ID: CAR19_HUMAN
Immunogen Region: 1-100
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CARD19 (NP_115686.3).
Immunogen Sequence: MTDQTYCDRLVQDTPFLTGH GRLSEQQVDRIILQLNRYYP QILTNKEAEKFRNPKASLRV RLCDLLSHLQRSGERDCQEF YRALYIHAQPLHSRLPSRHA
Tissue Specificity Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.
Function Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.
Protein Name Caspase Recruitment Domain-Containing Protein 19
Bcl10-Interacting Card Protein
Bincard
Cellular Localisation Isoform 1: Nucleus
Coexpression With Bcl10 Induced Translocation From Nucleus To Cytosol
Isoform 2: Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Mitochondrion Membrane
Alternative Antibody Names Anti-Caspase Recruitment Domain-Containing Protein 19 antibody
Anti-Bcl10-Interacting Card Protein antibody
Anti-Bincard antibody
Anti-CARD19 antibody
Anti-C9orf89 antibody

Information sourced from Uniprot.org

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