| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CARD19 |
| Gene ID: | 84270 |
| Uniprot ID: | CAR19_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CARD19 (NP_115686.3). |
| Immunogen Sequence: | MTDQTYCDRLVQDTPFLTGH GRLSEQQVDRIILQLNRYYP QILTNKEAEKFRNPKASLRV RLCDLLSHLQRSGERDCQEF YRALYIHAQPLHSRLPSRHA |
| Tissue Specificity | Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain. |
| Function | Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner. |
| Protein Name | Caspase Recruitment Domain-Containing Protein 19Bcl10-Interacting Card ProteinBincard |
| Cellular Localisation | Isoform 1: NucleusCoexpression With Bcl10 Induced Translocation From Nucleus To CytosolIsoform 2: Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinMitochondrion Membrane |
| Alternative Antibody Names | Anti-Caspase Recruitment Domain-Containing Protein 19 antibodyAnti-Bcl10-Interacting Card Protein antibodyAnti-Bincard antibodyAnti-CARD19 antibodyAnti-C9orf89 antibody |
Information sourced from Uniprot.org