| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CAPN10 |
| Gene ID: | 11132 |
| Uniprot ID: | CAN10_HUMAN |
| Immunogen Region: | 1-230 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human CAPN10 (NP_075571.1). |
| Immunogen Sequence: | MRAGRGATPARELFRDAAFP AADSSLFCDLSTPLAQFRED ITWRRPQEICATPRLFPDDP REGQVKQGLLGDCWFLCACA ALQKSRHLLDQVIPPGQPSW ADQEYRGSFTCRIWQFGRWV EVTTDDRLPCLAGRLCFSRC QREDVFWLPLLEKVYAKVHG SYEHLWAGQVADALVDLTGG LAERWNLKGVAGSGGQQDRP GRWEHRTCRQLLHLKDQCLI SCCVLSPRAG |
| Tissue Specificity | Detected in primary skeletal muscle cells (at protein level). Ubiquitous. |
| Function | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. May play a role in insulin-stimulated glucose uptake. |
| Protein Name | Calpain-10Calcium-Activated Neutral Proteinase 10Canp 10 |
| Database Links | Reactome: R-HSA-1474228 |
| Alternative Antibody Names | Anti-Calpain-10 antibodyAnti-Calcium-Activated Neutral Proteinase 10 antibodyAnti-Canp 10 antibodyAnti-CAPN10 antibodyAnti-KIAA1845 antibody |
Information sourced from Uniprot.org