Anti-CAMSAP1 antibody (350-650) (STJ11102934)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CAMSAP1 (350-650) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAMSAP1 |
| Gene ID | 157922 |
| Uniprot ID | CAMP1_HUMAN |
| Immunogen Region | 350-650 |
| Immunogen Sequence | KTVLHQKSSRPPVPISNATK RSFLGSPAAGTLAELQPPVQ LPAEGCHRHYLHPEEPEYLG KGTAAFSPSHPLLPLRQKQQ KSIQGEDIPDQRHRSNSLTR VDGQPRGAAIAWPEKKTRPA SQPTPFALHHAASCEVDPSS GDSISLARSISKDSLASNIV NLTPQNQPHPTATKSHGKSL LSNVSIEDEEEELVAIVRAD VVPQQADPEFPRASPRALGL TANARSPQGQLDTSESKPD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 350-650 of human CAMSAP1 (NP_056262.3). |
Additional Info
| Function | Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus-ends and stabilizes microtubules. Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization. In contrast to CAMSAP2 and CAMSAP3, tracks along the growing tips of minus-end microtubules without significantly affecting the polymerization rate: binds at the very tip of the microtubules minus-end and acts as a minus-end tracking protein (-TIP) that dissociates from microtubules after allowing tubulin incorporation. Through interaction with spectrin may regulate neurite outgrowth. |
| Protein Name | Calmodulin-Regulated Spectrin-Associated Protein 1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonAssociates With The Minus-End Of MicrotubulesIn Contrast To Camsap2 And Camsap3Does Not Form Stretches Of Decorated Microtubule Minus-Ends |
| Alternative Antibody Names | Anti-Calmodulin-Regulated Spectrin-Associated Protein 1 antibodyAnti-CAMSAP1 antibody |
Information sourced from Uniprot.org