| Tissue Specificity | Widely expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes. |
| Function | Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta. |
| Protein Name | Calcium/Calmodulin-Dependent Protein Kinase Type 1dCam Kinase I DeltaCam Kinase IdCam-Ki DeltaCamki DeltaCamkidCamki-Like Protein KinaseCklik |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicNuclear Localization Increases Upon Activation By Kcl Treatment In Hippocampal Neurons |
| Alternative Antibody Names | Anti-Calcium/Calmodulin-Dependent Protein Kinase Type 1d antibodyAnti-Cam Kinase I Delta antibodyAnti-Cam Kinase Id antibodyAnti-Cam-Ki Delta antibodyAnti-Camki Delta antibodyAnti-Camkid antibodyAnti-Camki-Like Protein Kinase antibodyAnti-Cklik antibodyAnti-CAMK1D antibodyAnti-CAMKID antibody |
Information sourced from Uniprot.org
![Confocal immunofluorescence analysis of HeLa cells using [KO Validated] HNRNPA2B1 Rabbit polyclonal antibody (STJ24063) at dilution of 1:400. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/99826/385443/STJ24063_1__97324.1713154337.jpg?c=1 "Confocal immunofluorescence analysis of HeLa cells using [KO Validated] HNRNPA2B1 Rabbit polyclonal antibody (STJ24063) at dilution of 1:400. Blue: DAPI for nuclear staining.")
