| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CADM3 (25-330) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CADM3 |
| Gene ID: |
57863 |
| Uniprot ID: |
CADM3_HUMAN |
| Immunogen Region: |
25-330 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 25-330 of human CADM3 (NP_001120645.1). |
| Immunogen Sequence: |
NLSQDDSQPWTSDETVVAGG TVVLKCQVKDHEDSSLQWSN PAQQTLYFGEKRALRDNRIQ LVTSTPHELSISISNVALAD EGEYTCSIFTMPVRTAKSLV TVLGIPQKPIITGYKSSLRE KDTATLNCQSSGSKPAARLT WRKGDQELHGEPTRIQEDPN GKTFTVSSSVTFQVTREDDG ASIVCSVNHESLKGADRSTS QRIEVLYTPTAMIRPDPPHP REGQKLLLHCEGRGNPVPQ |
| Tissue Specificity | Isoform 1 is expressed mainly in adult and fetal brain. Isoform 2 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum. |
| Function | Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions. |
| Protein Name | Cell Adhesion Molecule 3Brain Immunoglobulin ReceptorImmunoglobulin Superfamily Member 4bIgsf4bNectin-Like Protein 1Necl-1Synaptic Cell Adhesion Molecule 3Syncam3Tslc1-Like Protein 1Tsll1 |
| Database Links | Reactome: R-HSA-418990Reactome: R-HSA-420597 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell Junction |
| Alternative Antibody Names | Anti-Cell Adhesion Molecule 3 antibodyAnti-Brain Immunoglobulin Receptor antibodyAnti-Immunoglobulin Superfamily Member 4b antibodyAnti-Igsf4b antibodyAnti-Nectin-Like Protein 1 antibodyAnti-Necl-1 antibodyAnti-Synaptic Cell Adhesion Molecule 3 antibodyAnti-Syncam3 antibodyAnti-Tslc1-Like Protein 1 antibodyAnti-Tsll1 antibodyAnti-CADM3 antibodyAnti-IGSF4B antibodyAnti-NECL1 antibodyAnti-SYNCAM3 antibodyAnti-TSLL1 antibodyAnti-UNQ225 antibodyAnti-PRO258 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
