Anti-CACNA1F antibody (STJ13100823)

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STJ13100823-500
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Short Description :Rabbit polyclonal anti-CACNA1F for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/WB
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Purification:IgG purified
Dilution Range:IHC, WB. A concentration of 10-50 ug/ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.
Formulation:Lyophilised
Storage Instruction:Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol:CACNA1F
Gene ID:778
Uniprot ID:CAC1F_HUMAN
Immunogen:A synthetic peptide from human CACNA1F conjugated to blue carrier protein was used as the antigen.
Specificity:Specific for CACNA1F.
Function Isoform 1: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. Activates at more negative voltages and does not undergo calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarization. Isoform 4: Voltage-dependent L-type calcium channel activates at more hyperpolarized voltages and exhibits a robust calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarizations. Isoform 5: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Isoform 6: Voltage-dependent L-type calcium channel activates at more hyperpolarized voltages and exhibits a robust calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarizations.
Protein Name Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1f
Voltage-Gated Calcium Channel Subunit Alpha Cav1.4
Database Links
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1f antibody
Anti-Voltage-Gated Calcium Channel Subunit Alpha Cav1.4 antibody
Anti-CACNA1F antibody
Anti-CACNAF1 antibody

Information sourced from Uniprot.org

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