| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CA12 |
| Gene ID: | 771 |
| Uniprot ID: | CAH12_HUMAN |
| Immunogen Region: | 25-301 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-301 of human CA12 (NP_001209.1). |
| Immunogen Sequence: | APVNGSKWTYFGPDGENSWS KKYPSCGGLLQSPIDLHSDI LQYDASLTPLEFQGYNLSAN KQFLLTNNGHSVKLNLPSDM HIQGLQSRYSATQLHLHWGN PNDPHGSEHTVSGQHFAAEL HIVHYNSDLYPDASTASNKS EGLAVLAVLIEMGSFNPSYD KIFSHLQHVKYKGQEAFVPG FNIEELLPERTAEYYRYRGS LTTPPCNPTVLWTVFRNPVQ ISQEQLLALETALYCTHMD |
| Tissue Specificity | Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. Expressed in sweat glands and bronchiolar epithelium. |
| Function | Reversible hydration of carbon dioxide. |
| Protein Name | Carbonic Anhydrase 12Carbonate Dehydratase XiiCarbonic Anhydrase XiiCa-XiiTumor Antigen Hom-Rcc-3.1.3 |
| Database Links | Reactome: R-HSA-1475029 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Carbonic Anhydrase 12 antibodyAnti-Carbonate Dehydratase Xii antibodyAnti-Carbonic Anhydrase Xii antibodyAnti-Ca-Xii antibodyAnti-Tumor Antigen Hom-Rcc-3.1.3 antibodyAnti-CA12 antibody |
Information sourced from Uniprot.org