Anti-C3AR1 antibody (1-100) (STJ11105428)

Name: Anti-C3AR1 antibody (1-100) (STJ11105428)
SKU: STJ11105428
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11105428

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Short Description	Rabbit polyclonal C3a Anaphylatoxin Chemotactic Receptor (1-100) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:1000-1:5000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	C3AR1
Gene ID	719
Uniprot ID	C3AR_HUMAN
Immunogen Region	1-100
Immunogen Sequence	MASFSAETNSTDLLSQPWNE PPVILSMVILSLTFLLGLPG NGLVLWVAGLKMQRTVNTIW FLHLTLADLLCCLSLPFSLA HLALQGQWPYGRFLCKLIPS
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human C3AR1 (NP_004045.1).

Tissue Specificity	Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.
Post Translational Modifications	Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin. O-glycosylated.
Function	Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
Protein Name	C3a Anaphylatoxin Chemotactic Receptor C3ar C3a-R
Database Links	Reactome: R-HSA-375276 Reactome: R-HSA-418594 Reactome: R-HSA-6798695 Reactome: R-HSA-9660826 Reactome: R-HSA-977606
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-C3a Anaphylatoxin Chemotactic Receptor antibody Anti-C3ar antibody Anti-C3a-R antibody Anti-C3AR1 antibody Anti-AZ3B antibody Anti-C3R1 antibody Anti-HNFAG09 antibody

Information sourced from Uniprot.org