| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-C2GnT-M (273-284) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:2000. WB: Approx. 50kDa band observed in Human Lymph Node lysates (calculated MW of 50.9kDa according to NP_004742.1). In transfected HEK293 transiently expressing GCNT3 a band of approx. 55kDa i |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | GCNT3 |
| Gene ID: | 9245 |
| Uniprot ID: | GCNT3_HUMAN |
| Immunogen Region: | 273-284 |
| Accession Number: | NP_004742.1 |
| Immunogen Sequence: | RDTLHLTNKKKD |
| Post Translational Modifications | N-glycosylated. |
| Function | Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. |
| Protein Name | Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 C2gnt-Mucin Type C2gnt-M Hc2gnt-M Core 2/Core 4 Beta-1 -6-N-Acetylglucosaminyltransferase C2/4gnt |
| Database Links | Reactome: R-HSA-913709 |
| Cellular Localisation | Golgi Apparatus Membrane Single-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 antibody Anti-C2gnt-Mucin Type antibody Anti-C2gnt-M antibody Anti-Hc2gnt-M antibody Anti-Core 2/Core 4 Beta-1 -6-N-Acetylglucosaminyltransferase antibody Anti-C2/4gnt antibody Anti-GCNT3 antibody |
Information sourced from Uniprot.org