Anti-C1QTNF12 antibody (193-243 aa) (STJ195780)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human F132A at the amino acid range 193-243
General Information
| Short Description | Rabbit polyclonal anti-Adipolin (193-243 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | C1QTNF12 |
| Gene ID | 388581 |
| Uniprot ID | ADIPL_HUMAN |
| Immunogen | Synthesized peptide derived from the human F132A at the amino acid range 193-243 |
| Immunogen Region | 193-243 aa |
| Specificity | This antibody detects endogenous levels of F132A at Human/Mouse |
Additional Info
| Post Translational Modifications | Processed into Adipolin fC1QTNF12 and Adipolin gC1QTNF12 by FURIN. Insulin enhances endogenous C1QTNF12 cleavage. |
| Function | Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue. |
| Protein Name | AdipolinAdipose-Derived Insulin-Sensitizing FactorC1q And Tnf Related Protein 12Complement C1q Tumor Necrosis Factor-Related Protein 12 Cleaved Into - Adipolin Fc1qtnf12Adipolin Fctrp12Adipolin Full-Length Form - Adipolin Gc1qtnf12Adipolin Cleaved FormAdipolin Gctrp12 |
| Database Links | |
| Cellular Localisation | Adipolin Fc1qtnf12: SecretedAdipolin Gc1qtnf12: SecretedIn Sera Is The Predominant Form |
| Alternative Antibody Names | Anti-Adipolin antibodyAnti-Adipose-Derived Insulin-Sensitizing Factor antibodyAnti-C1q And Tnf Related Protein 12 antibodyAnti-Complement C1q Tumor Necrosis Factor-Related Protein 12 Cleaved Into - Adipolin Fc1qtnf12 antibodyAnti-Adipolin Fctrp12 antibodyAnti-Adipolin Full-Length Form - Adipolin Gc1qtnf12 antibodyAnti-Adipolin Cleaved Form antibodyAnti-Adipolin Gctrp12 antibodyAnti-C1QTNF12 antibodyAnti-C1QDC2 antibodyAnti-CTRP12 antibodyAnti-FAM132A antibody |
Information sourced from Uniprot.org