Anti-C14orf166 antibody (1-244) (STJ26297)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal C14orf166 (1-244) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RTRAF |
| Gene ID | 51637 |
| Uniprot ID | RTRAF_HUMAN |
| Immunogen Region | 1-244 |
| Immunogen Sequence | MFRRKLTALDYHNPAGFNCK DETEFRNFIVWLEDQKIRHY KIEDRGNLRNIHSSDWPKFF EKYLRDVNCPFKIQDRQEAI DWLLGLAVRLEYGDNAEKYK DLVPDNSKTADNATKNAEPL INLDVNNPDFKAGVMALANL LQIQRHDDYLVMLKAIRILV QERLTQDAVAKANQTKEGLP VALDKHILGFDTGDAVLNEA AQILRLLHIEELRELQTKIN EAIVAVQAIIADPKTDHRL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human C14orf166 (NP_057123.1). |
Additional Info
| Tissue Specificity | Widely expressed. Expressed at high level in heart and skeletal muscle. Expressed at intermediate level in liver, pancreas, fetal brain and fetal lung. Weakly expressed in adult brain, adult lung, placenta, fetal liver and fetal kidney. Overexpressed in many brain tumors. |
| Function | RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Component of the tRNA-splicing ligase complex and is required for tRNA ligation. May be required for RNA transport. (Microbial infection) In case of infection by influenza virus A (IVA), is involved in viral replication. |
| Protein Name | Rna Transcription - Translation And Transport Factor ProteinCle7 HomologCleHcle |
| Database Links | Reactome: R-HSA-6784531 |
| Cellular Localisation | NucleusCytoplasmCytosolPerinuclear RegionCytoskeletonMicrotubule Organizing CenterCentrosomeMay Localize At The Centrosome During MitosisShuttles Between The Cytosol And The Nucleus: Enters Into The Nucleus In Case Of Active Transcription While It Accumulates In Cytosol When Transcription Level Is Low(Microbial Infection) Following Influenza A Virus (Iav) InfectionIncluded In Influenza A Virions Via Its Association With Packaged Viral Ribonucleoproteins (Vrnp) In The Nucleus And Cytoplasm |
| Alternative Antibody Names | Anti-Rna Transcription - Translation And Transport Factor Protein antibodyAnti-Cle7 Homolog antibodyAnti-Cle antibodyAnti-Hcle antibodyAnti-RTRAF antibodyAnti-C14orf166 antibodyAnti-CGI-99 antibody |
Information sourced from Uniprot.org