Host: |
Rabbit |
Applications: |
IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-C12orf10 (48-376) is suitable for use in Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MYG1 |
Gene ID: |
60314 |
Uniprot ID: |
MYG1_HUMAN |
Immunogen Region: |
48-376 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 48-376 of human C12orf10 (NP_067653.3). |
Immunogen Sequence: |
GTHNGTFHCDEALACALLRL LPEYRDAEIVRTRDPEKLAS CDIVVDVGGEYDPRRHRYDH HQRSFTETMSSLSPGKPWQT KLSSAGLIYLHFGHKLLAQL LGTSEEDSMVGTLYDKMYEN FVEEVDAVDNGISQWAEGEP RYALTTTLSARVARLNPTWN HPDQDTEAGFKRAMDLVQEE FLQRLDFYQHSWLPARALVE EALAQRFQVDPSGEIVELAK GACPWKEHLYHLESGLSPP |
Tissue Specificity | Ubiquitously expressed, with highest levels in testis. |
Function | 3'-5' RNA exonuclease which cleaves in situ on specific transcripts in both nucleus and mitochondrion. Involved in regulating spatially segregated organellar RNA processing, acts as a coordinator of nucleo-mitochondrial crosstalk. In nucleolus, processes pre-ribosomal RNA involved in ribosome assembly and alters cytoplasmic translation. In mitochondrial matrix, processes 3'-termini of the mito-ribosomal and messenger RNAs and controls translation of mitochondrial proteins (Probable). |
Protein Name | Myg1 Exonuclease |
Cellular Localisation | NucleusNucleoplasmMitochondrion MatrixNucleolus |
Alternative Antibody Names | Anti-Myg1 Exonuclease antibodyAnti-MYG1 antibodyAnti-C12orf10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance