Anti-Butyrylcholinesterase antibody (500-602) [S6MR] (STJ11103636)

Name: Anti-Butyrylcholinesterase antibody (500-602) [S6MR] (STJ11103636)
SKU: STJ11103636
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11103636

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Rabbit monoclonal Butyrylcholinesterase (500-602) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S6MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	BCHE
Gene ID	590
Uniprot ID	CHLE_HUMAN
Immunogen Region	500-602
Immunogen Sequence	ANFAKYGNPNETQNNSTSWP VFKSTEQKYLTLNTESTRIM TKLRAQQCRFWTSFFPKVLE MTGNIDEAEWEWKAGFHRWN NYMMDWKNQFNDYTSKKESC VGL
Specificity	A synthetic peptide corresponding to a sequence within amino acids 500-602 of human Butyrylcholinesterase (P06276).

Tissue Specificity	Detected in blood plasma (at protein level). Present in most cells except erythrocytes.
Post Translational Modifications	N-glycosylated. No other PTM detected. The major N-glycan structures are of the complex diantennary type with 1 and 2 N-acetylneuraminic acid molecules (Neu5Ac) making up approximately 33% and 47% of the total N-glycans, respectively. Only low amounts of fucosylated diantennary N-glycans are detected (approximately 2%). Triantennary N-glycans with or without fucose amount to approximately 13%, whereas 5% of the total N-glycans are of the oligomannosidic or hybrid type.
Function	Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.
Protein Name	Cholinesterase Acylcholine Acylhydrolase Butyrylcholine Esterase Choline Esterase Ii Pseudocholinesterase
Database Links	Reactome: R-HSA-112311 Reactome: R-HSA-1483191 Reactome: R-HSA-422085 Reactome: R-HSA-9749641
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Cholinesterase antibody Anti-Acylcholine Acylhydrolase antibody Anti-Butyrylcholine Esterase antibody Anti-Choline Esterase Ii antibody Anti-Pseudocholinesterase antibody Anti-BCHE antibody Anti-CHE1 antibody

Information sourced from Uniprot.org