| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BRD9 |
| Gene ID: | 65980 |
| Uniprot ID: | BRD9_HUMAN |
| Immunogen Region: | 274-597 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 274-597 of human BRD9 (NP_076413.3). |
| Immunogen Sequence: | REVISCMFEPEGNACSLTDS TAEEHVLALVEHAADEARDR INRFLPGGKMGYLKRNGDGS LLYSVVNTAEPDADEEETHP VDLSSLSSKLLPGFTTLGFK DERRNKVTFLSSATTALSMQ NNSVFGDLKSDEMELLYSAY GDETGVQCALSLQEFVKDAG SYSKKVVDDLLDQITGGDHS RTLFQLKQRRNVPMKPPDEA KVGDTLGDSSSSVLEFMSMK SYPDVSVDISMLSSLGKVK |
| Function | Plays a role in chromatin remodeling and regulation of transcription. Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR). |
| Protein Name | Bromodomain-Containing Protein 9Rhabdomyosarcoma Antigen Mu-Rms-40.8 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Bromodomain-Containing Protein 9 antibodyAnti-Rhabdomyosarcoma Antigen Mu-Rms-40.8 antibodyAnti-BRD9 antibodyAnti-UNQ3040 antibodyAnti-PRO9856 antibody |
Information sourced from Uniprot.org