| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BMS1 |
| Gene ID: | 9790 |
| Uniprot ID: | BMS1_HUMAN |
| Immunogen Region: | 600-900 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human BMS1 (NP_055568.3). |
| Immunogen Sequence: | LSAEEEDSENEEAIRKKLSK PSQVSSGQKLGPQNFIDETS DIENLLKEEEDYKEENNDSK ETSGALKWKEDLSRKAAEAF LRQQQAAPNLRKLIYGTVTE DNEEEDDDTLEELGGLFRVN QPDRECKHKADSLDCSRFLV EAPHDWDLEEVMNSIRDCFV TGKWEDDKDAAKVLAEDEEL YGDFEDLETGDVHKGKSGPN TQNEDIEKEVKEEIDPDEEE SAKKKHLDKKRKLKEMFDA |
| Function | GTPase required for the synthesis of 40S ribosomal subunits and for processing of pre-ribosomal RNA (pre-rRNA) at sites A0, A1, and A2. Controls access of pre-rRNA intermediates to RCL1 during ribosome biogenesis by binding RCL1 in a GTP-dependent manner, and delivering it to pre-ribosomes. GTP-binding and/or GTP hydrolysis may induce conformational rearrangements within the BMS1-RCL1 complex allowing the interaction of RCL1 with its RNA substrate. Required for RCL1 import into the nucleus. |
| Protein Name | Ribosome Biogenesis Protein Bms1 HomologRibosome Assembly Protein Bms1 Homolog |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Ribosome Biogenesis Protein Bms1 Homolog antibodyAnti-Ribosome Assembly Protein Bms1 Homolog antibodyAnti-BMS1 antibodyAnti-BMS1L antibodyAnti-KIAA0187 antibody |
Information sourced from Uniprot.org
