Anti-BEX3 antibody (1-80 aa) (STJ192330)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 1-80
General Information
| Short Description | Rabbit polyclonal anti-Protein BEX3 (1-80 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BEX3 |
| Gene ID | 27018 |
| Uniprot ID | BEX3_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 1-80 |
| Immunogen Region | 1-80 aa |
| Specificity | BEX3 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Ubiquitinated. Degraded by the proteasome. |
| Function | May be a signaling adapter molecule involved in NGFR/p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates. |
| Protein Name | Protein Bex3Brain-Expressed X-Linked Protein 3Nerve Growth Factor Receptor-Associated Protein 1Ovarian Granulosa Cell 13.0 Kda Protein Hgr74P75ntr-Associated Cell Death Executor |
| Database Links | Reactome: R-HSA-205025 |
| Cellular Localisation | NucleusCytoplasmCytosolShuttles Between The Cytoplasm And The NucleusAssociates With Replicating Mitochondria |
| Alternative Antibody Names | Anti-Protein Bex3 antibodyAnti-Brain-Expressed X-Linked Protein 3 antibodyAnti-Nerve Growth Factor Receptor-Associated Protein 1 antibodyAnti-Ovarian Granulosa Cell 13.0 Kda Protein Hgr74 antibodyAnti-P75ntr-Associated Cell Death Executor antibodyAnti-BEX3 antibodyAnti-DXS6984E antibodyAnti-NADE antibodyAnti-NGFRAP1 antibody |
Information sourced from Uniprot.org