Western blot analysis of various lysates using Beta 1-Adrenergic Receptor Rabbit polyclonal antibody (STJ11103471) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.

Anti-Beta 1-Adrenergic Receptor antibody (350-450) (STJ11103471)

SKU:
STJ11103471
£112.50 - £524.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADRB1
Gene ID: 153
Uniprot ID: ADRB1_HUMAN
Immunogen Region: 350-450
Specificity: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Beta 1-Adrenergic Receptor (NP_000675.1).
Immunogen Sequence: HRELVPDRLFVFFNWLGYAN SAFNPIIYCRSPDFRKAFQG LLCCARRAARRRHATHGDRP RASGCLARPGPPPSPGAASD DDDDDVVGATPPARLLEPWA G
Post Translational Modifications Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.
Function Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors.
Protein Name Beta-1 Adrenergic Receptor
Beta-1 Adrenoreceptor
Beta-1 Adrenoceptor
Database Links Reactome: R-HSA-390696
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Early Endosome
Colocalizes With Rapgef2 At The Plasma Membrane
Localized At The Plasma Membrane
Found In The Golgi Upon Gopc Overexpression
Alternative Antibody Names Anti-Beta-1 Adrenergic Receptor antibody
Anti-Beta-1 Adrenoreceptor antibody
Anti-Beta-1 Adrenoceptor antibody
Anti-ADRB1 antibody
Anti-ADRB1R antibody
Anti-B1AR antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ11103081 Anti-GABA A Receptor beta 1 antibody (350-450) [S1MR] (STJ11103081) Rabbit Monoclonal Human/Mouse/Rat WB/ELISA
STJ117382 Anti-MMEL1 antibody (350-450) (STJ117382) Rabbit Polyclonal Human WB/ELISA
STJ117409 Anti-LIPH antibody (350-450) (STJ117409) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJ112150 Anti-GABRR2 antibody (350-450) (STJ112150) Rabbit Polyclonal Human/Mouse WB/ELISA
STJ501172 Anti-KCNJ5 antibody (350-450) (STJ501172) Rabbit Polyclonal Human/Mouse/Rat ELISA/IP/WB
STJ11104256 Anti-DET1 antibody (350-450) (STJ11104256) Rabbit Polyclonal A.thaliana WB/ELISA
!