| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BCAT1 |
| Gene ID: | 586 |
| Uniprot ID: | BCAT1_HUMAN |
| Immunogen Region: | 20-190 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human BCAT1 (NP_005495.2). |
| Immunogen Sequence: | EVVGTFKAKDLIVTPATILK EKPDPNNLVFGTVFTDHMLT VEWSSEFGWEKPHIKPLQNL SLHPGSSALHYAVELFEGLK AFRGVDNKIRLFQPNLNMDR MYRSAVRATLPVFDKEELLE CIQQLVKLDQEWVPYSTSAS LYIRPTFIGTEPSLGVKKPT KALLFVLLSPV |
| Tissue Specificity | During embryogenesis, expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma. |
| Function | Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. |
| Protein Name | Branched-Chain-Amino-Acid Aminotransferase - CytosolicBcat(C |
| Database Links | Reactome: R-HSA-70895 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Branched-Chain-Amino-Acid Aminotransferase - Cytosolic antibodyAnti-Bcat(C antibodyAnti-BCAT1 antibodyAnti-BCT1 antibodyAnti-ECA39 antibody |
Information sourced from Uniprot.org