| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BATF3 |
| Gene ID: | 55509 |
| Uniprot ID: | BATF3_HUMAN |
| Immunogen Region: | 1-127 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human BATF3 (NP_061134.1). |
| Immunogen Sequence: | MSQGLPAAGSVLQRSVAAPG NQPQPQPQQQSPEDDDRKVR RREKNRVAAQRSRKKQTQKA DKLHEEYESLEQENTMLRRE IGKLTEELKHLTEALKEHEK MCPLLLCPMNFVPVPPRPDP VAGCLPR |
| Function | AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGACGTCA-3' and regulates expression of target genes. |
| Protein Name | Basic Leucine Zipper Transcriptional Factor Atf-Like 3B-Atf-321 Kda Small Nuclear Factor Isolated From T-CellsJun Dimerization Protein P21snft |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Basic Leucine Zipper Transcriptional Factor Atf-Like 3 antibodyAnti-B-Atf-3 antibodyAnti-21 Kda Small Nuclear Factor Isolated From T-Cells antibodyAnti-Jun Dimerization Protein P21snft antibodyAnti-BATF3 antibodyAnti-SNFT antibody |
Information sourced from Uniprot.org