| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (35-84 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300 ELISA 1:5000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | B3GAT1 |
| Gene ID: | 27087 |
| Uniprot ID: | B3GA1_HUMAN |
| Immunogen Region: | 35-84 aa |
| Specificity: | CD57 Polyclonal Antibody detects endogenous levels of CD57 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CD57 at the amino acid range 35-84 |
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
| Protein Name | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 Beta-1 -3-Glucuronyltransferase 1 Glucuronosyltransferase P Glcat-P Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase Glcuat-P |
| Database Links | Reactome: R-HSA-1971475 |
| Cellular Localisation | Isoform 1: Golgi Apparatus Membrane Single-Pass Type Ii Membrane Protein Secreted Isoform 2: Golgi Apparatus Membrane Endoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 antibody Anti-Beta-1 -3-Glucuronyltransferase 1 antibody Anti-Glucuronosyltransferase P antibody Anti-Glcat-P antibody Anti-Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase antibody Anti-Glcuat-P antibody Anti-B3GAT1 antibody Anti-GLCATP antibody |
Information sourced from Uniprot.org