Anti-AZU1 antibody (51-100 aa) (STJ192602)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 51-100
General Information
| Short Description | Rabbit polyclonal anti-Azurocidin (51-100 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AZU1 |
| Gene ID | 566 |
| Uniprot ID | CAP7_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 51-100 |
| Immunogen Region | 51-100 aa |
| Specificity | CAP7 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria.this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G. |
| Protein Name | AzurocidinCationic Antimicrobial Protein Cap37Heparin-Binding ProteinHbpHhbp |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasmic Granule MembranePeripheral Membrane ProteinCytoplasmic SideLocalizes To Azurophil Granules Of Neutrophil GranulocytesAlso Called Primary GranulesThese Specialized Lysosomes Of The Neutrophil Formed Early During Promyelocyte Development Store Antibacterial Proteins And Peptides |
| Alternative Antibody Names | Anti-Azurocidin antibodyAnti-Cationic Antimicrobial Protein Cap37 antibodyAnti-Heparin-Binding Protein antibodyAnti-Hbp antibodyAnti-Hhbp antibodyAnti-AZU1 antibody |
Information sourced from Uniprot.org