Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-5-azacytidine-induced protein 2 (10-59) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
AZI2 |
Gene ID: |
64343 |
Uniprot ID: |
AZI2_HUMAN |
Immunogen Region: |
10-59 |
Specificity: |
Nap1 Polyclonal Antibody detects endogenous levels of Nap1 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human AZI2. AA range:10-59 |
Tissue Specificity | Widely expressed. Abundant expression seen in the pancreas and testis. |
Post Translational Modifications | Ubiquitinated via 'Lys-48'-linked polyubiquitination by TRIM38, leading to its degradation. |
Function | Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1. |
Protein Name | 5-Azacytidine-Induced Protein 2Nf-Kappa-B-Activating Kinase-Associated Protein 1Nak-Associated Protein 1Nap1Tilp |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-5-Azacytidine-Induced Protein 2 antibodyAnti-Nf-Kappa-B-Activating Kinase-Associated Protein 1 antibodyAnti-Nak-Associated Protein 1 antibodyAnti-Nap1 antibodyAnti-Tilp antibodyAnti-AZI2 antibodyAnti-NAP1 antibodyAnti-TBKBP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance