| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ATP5B (230-529) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATP5F1B |
| Gene ID: |
506 |
| Uniprot ID: |
ATPB_HUMAN |
| Immunogen Region: |
230-529 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 230-529 of human ATPB (NP_001677.2). |
| Immunogen Sequence: |
YSVFAGVGERTREGNDLYHE MIESGVINLKDATSKVALVY GQMNEPPGARARVALTGLTV AEYFRDQEGQDVLLFIDNIF RFTQAGSEVSALLGRIPSAV GYQPTLATDMGTMQERITTT KKGSITSVQAIYVPADDLTD PAPATTFAHLDATTVLSRAI AELGIYPAVDPLDSTSRIMD PNIVGSEHYDVARGVQKILQ DYKSLQDIIAILGMDELSEE DKLTVSRARKIQRFLSQPF |
| Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. |
| Protein Name | Atp Synthase Subunit Beta - MitochondrialAtp Synthase F1 Subunit Beta |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-163210Reactome: R-HSA-2151201Reactome: R-HSA-8949613 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Atp Synthase Subunit Beta - Mitochondrial antibodyAnti-Atp Synthase F1 Subunit Beta antibodyAnti-ATP5F1B antibodyAnti-ATP5B antibodyAnti-ATPMB antibodyAnti-ATPSB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
