| Function | Forms bile acid-gated sodium channels and may play a role in bile acid-dependent absorption and secretion by epithelial cells of the bile ducts. Displays high selectivity for sodium ions but can also permit the permeation of other cations (Probable). The gating could be indirect and the consequence of alterations of the membrane environment of the channel by bile acids. As a sodium channel of type II unipolar brush cells of the vestibulocerebellum, controlling the electrical activity of these cells, could play a role in motor coordination and balance. |
| Protein Name | Bile Acid-Sensitive Ion ChannelBasicAcid-Sensing Ion Channel Subunit Family Member 5Amiloride-Sensitive Cation Channel 5 - IntestinalHuman Intestine Na(+ ChannelHinac |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Bile Acid-Sensitive Ion Channel antibodyAnti-Basic antibodyAnti-Acid-Sensing Ion Channel Subunit Family Member 5 antibodyAnti-Amiloride-Sensitive Cation Channel 5 - Intestinal antibodyAnti-Human Intestine Na(+ Channel antibodyAnti-Hinac antibodyAnti-ASIC5 antibodyAnti-ACCN5 antibody |
Information sourced from Uniprot.org
