| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Histone-lysine N-methyltransferase ASH1L (1323-1373 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ASH1L |
| Gene ID: | 55870 |
| Uniprot ID: | ASH1L_HUMAN |
| Immunogen Region: | 1323-1373 aa |
| Specificity: | This antibody detects endogenous levels of human ASH1L |
| Immunogen: | Synthesized peptide derived from the human ASH1L at the amino acid range 1323-1373 |
| Post Translational Modifications | Methylated at Gln-1220 by N6AMT1. |
| Function | Histone methyltransferase specifically trimethylating 'Lys-36' of histone H3 forming H3K36me3. Also monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro. The physiological significance of the H3K9me1 activity is unclear. |
| Protein Name | Histone-Lysine N-Methyltransferase Ash1lAsh1-Like ProteinHuash1Absent Small And Homeotic Disks Protein 1 HomologLysine N-Methyltransferase 2h |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | NucleusCell JunctionTight JunctionChromosomeThe Relevance Of Tight Junction Localization Is However Unclear |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase Ash1l antibodyAnti-Ash1-Like Protein antibodyAnti-Huash1 antibodyAnti-Absent Small And Homeotic Disks Protein 1 Homolog antibodyAnti-Lysine N-Methyltransferase 2h antibodyAnti-ASH1L antibodyAnti-KIAA1420 antibodyAnti-KMT2H antibody |
Information sourced from Uniprot.org