Anti-ASH1L antibody (1323-1373 aa) (STJ197834)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ASH1L at the amino acid range 1323-1373
General Information
| Short Description | Rabbit polyclonal anti-Histone-lysine N-methyltransferase ASH1L (1323-1373 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ASH1L |
| Gene ID | 55870 |
| Uniprot ID | ASH1L_HUMAN |
| Immunogen | Synthesized peptide derived from the human ASH1L at the amino acid range 1323-1373 |
| Immunogen Region | 1323-1373 aa |
| Specificity | This antibody detects endogenous levels of human ASH1L |
Additional Info
| Post Translational Modifications | Methylated at Gln-1220 by N6AMT1. |
| Function | Histone methyltransferase specifically trimethylating 'Lys-36' of histone H3 forming H3K36me3. Also monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro. The physiological significance of the H3K9me1 activity is unclear. |
| Protein Name | Histone-Lysine N-Methyltransferase Ash1lAsh1-Like ProteinHuash1Absent Small And Homeotic Disks Protein 1 HomologLysine N-Methyltransferase 2h |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | NucleusCell JunctionTight JunctionChromosomeThe Relevance Of Tight Junction Localization Is However Unclear |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase Ash1l antibodyAnti-Ash1-Like Protein antibodyAnti-Huash1 antibodyAnti-Absent Small And Homeotic Disks Protein 1 Homolog antibodyAnti-Lysine N-Methyltransferase 2h antibodyAnti-ASH1L antibodyAnti-KIAA1420 antibodyAnti-KMT2H antibody |
Information sourced from Uniprot.org