| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Asialoglycoprotein receptor 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ASGR1 |
| Gene ID: |
432 |
| Uniprot ID: |
ASGR1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of ASGR1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human ASGR1 |
| Post Translational Modifications | Phosphorylated on a cytoplasmic Ser residue. |
| Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
| Protein Name | Asialoglycoprotein Receptor 1Asgp-R 1Asgpr 1C-Type Lectin Domain Family 4 Member H1Hepatic Lectin H1Hl-1 |
| Database Links | Reactome: R-HSA-446203 |
| Cellular Localisation | Isoform H1a: MembraneSingle-Pass Type Ii Membrane ProteinIsoform H1b: Secreted |
| Alternative Antibody Names | Anti-Asialoglycoprotein Receptor 1 antibodyAnti-Asgp-R 1 antibodyAnti-Asgpr 1 antibodyAnti-C-Type Lectin Domain Family 4 Member H1 antibodyAnti-Hepatic Lectin H1 antibodyAnti-Hl-1 antibodyAnti-ASGR1 antibodyAnti-CLEC4H1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
