| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ankyrin repeat and SOCS box protein 9 (169-219 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ASB9 |
| Gene ID: | 140462 |
| Uniprot ID: | ASB9_HUMAN |
| Immunogen Region: | 169-219 aa |
| Specificity: | This antibody detects endogenous levels of ASB9 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human ASB9 at the amino acid range 169-219 |
| Function | Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The ECS(ASB9) complex catalyzes ubiquitination of creatine kinases CKB and CKMT1A. Isoform 2: Does not interact with the Elongin BC complex, likely to be a negative regulator of isoform 1. |
| Protein Name | Ankyrin Repeat And Socs Box Protein 9Asb-9 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Ankyrin Repeat And Socs Box Protein 9 antibodyAnti-Asb-9 antibodyAnti-ASB9 antibody |
Information sourced from Uniprot.org