Anti-ARRDC3 antibody (365-414 aa) (STJ91705)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ARRDC3 at the amino acid range 365-414
General Information
| Short Description | Rabbit polyclonal anti-Arrestin domain-containing protein 3 (365-414 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARRDC3 |
| Gene ID | 57561 |
| Uniprot ID | ARRD3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ARRDC3 at the amino acid range 365-414 |
| Immunogen Region | 365-414 aa |
| Specificity | ARRDC3 Polyclonal Antibody detects endogenous levels of ARRDC3 protein. |
Additional Info
| Function | Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes. |
| Protein Name | Arrestin Domain-Containing Protein 3Tbp-2-Like Inducible Membrane ProteinTlimp |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinCytoplasmic SideLysosomeEndosomeEarly EndosomeAssociated With Plasma MembraneAs Well As With Endosomes And Lysosomes During Endocytosis |
| Alternative Antibody Names | Anti-Arrestin Domain-Containing Protein 3 antibodyAnti-Tbp-2-Like Inducible Membrane Protein antibodyAnti-Tlimp antibodyAnti-ARRDC3 antibodyAnti-KIAA1376 antibody |
Information sourced from Uniprot.org