Anti-Arl13b antibody [N295B/66] (STJA0021090)

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STJA0021090
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Host: Mouse
Applications: IHC/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Arl13b is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : N295B/66
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: Arl13b
Gene ID: 68146
Uniprot ID: AR13B_MOUSE
Post Translational Modifications Sumoylation is required for PKD2 entry into cilium.
Function Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it.the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. Plays a role in ciliar trafficking of phosphatidylinositol phosphatase INPP5E in ciliogenesis. May regulate ARF6- and RAB22A-dependent endocytic recycling traffic.
Protein Name Adp-Ribosylation Factor-Like Protein 13b
Adp-Ribosylation Factor-Like Protein 2-Like 1
Arl2-Like Protein 1
Protein Hennin
Database Links Reactome: R-MMU-5624958
Reactome: -MMU-9013406
Reactome: -MMU-9646399
Cellular Localisation Cell Projection
Cilium Membrane
Lipid-Anchor
Cilium
Associates With The Cilium Membrane Via Palmitoylation
Localizes To Proximal Ciliary Membranes
To An Inversin-Like Subciliary Membrane Compartment
Excluding The Transition Zone
Alternative Antibody Names Anti-Adp-Ribosylation Factor-Like Protein 13b antibody
Anti-Adp-Ribosylation Factor-Like Protein 2-Like 1 antibody
Anti-Arl2-Like Protein 1 antibody
Anti-Protein Hennin antibody
Anti-Arl13b antibody
Anti-Arl2l1 antibody

Information sourced from Uniprot.org