Anti-AREG antibody (20-252) (STJ114553)

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STJ114553
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Short Description :Rabbit polyclonal AREG (20-252) antibody for use in IF, ICC and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IF/ICC/ELISA
Host:Rabbit
Reactivity:Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:AREG
Gene ID:374
Uniprot ID:AREG_HUMAN
Immunogen Region:20-252
Immunogen Sequence:SGHYAAGLDLNDTYSGKREP FSGDHSADGFEVTSRSEMSS GSEISPVSEMPSSSEPSSGA DYDYSEEYDNEPQIPGYIVD DSVRVEQVVKPPQNKTESEN TSDKPKRKKKGGKNGKNRRN RKKKNPCNAEFQNFCIHGEC KYIEHLEAVTCKCQQEYFGE RCGEKSMKTHSMIDSSLSKI ALAAIAAFMSAVILTAVAVI TVQLRRQYVRKYEGEAEERK KLRQENGNVHAIA
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 20-252 of human AREG (NP_001648.1).
Function Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Protein Name Amphiregulin
Ar
Colorectum Cell-Derived Growth Factor
Crdgf
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-177929
Reactome: R-HSA-179812
Reactome: R-HSA-180292
Reactome: R-HSA-180336
Reactome: R-HSA-182971
Reactome: R-HSA-204005
Reactome: R-HSA-212718
Reactome: R-HSA-2219530
Reactome: R-HSA-5638303
Reactome: R-HSA-5673001
Reactome: R-HSA-5694530
Reactome: R-HSA-6811558
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Reactome: R-HSA-9009391
Reactome: R-HSA-9634638
Reactome: R-HSA-9818030
Cellular Localisation Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Amphiregulin antibody
Anti-Ar antibody
Anti-Colorectum Cell-Derived Growth Factor antibody
Anti-Crdgf antibody
Anti-AREG antibody
Anti-AREGB antibody
Anti-SDGF antibody

Information sourced from Uniprot.org