| Host: |
Rabbit |
| Applications: |
ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: |
Bovine/Human/Mouse/Rat/Sheep |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AQP3 (200-250) is suitable for use in ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
FITC |
| Isotype: |
IgG |
| Formulation: |
Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: |
Affinity Purified |
| Concentration: |
0.50-0.57 µg/µl |
| Dilution Range: |
WB: 1:500ELISA: 1:10, 000IP: 1:200IHC: 1:100ICC: 1:100IF: 1:100 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Aqp3 |
| Gene ID: |
65133 |
| Uniprot ID: |
AQP3_RAT |
| Immunogen Region: |
200-250 |
| Immunogen: |
Synthetic peptide taken within amino acid region 200-250 on rat Aquaporin 3 protein. |
| Tissue Specificity | Detected in kidney medulla and papilla, in collecting duct cells. Detected in colon. |
| Function | Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair. In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance. |
| Protein Name | Aquaporin-3Aqp-331.4 Kda Water Channel ProteinAquaglyceroporin-3 |
| Database Links | Reactome: R-RNO-432040Reactome: -RNO-432047 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell Membrane |
| Alternative Antibody Names | Anti-Aquaporin-3 antibodyAnti-Aqp-3 antibodyAnti-31.4 Kda Water Channel Protein antibodyAnti-Aquaglyceroporin-3 antibodyAnti-Aqp3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
