| Host: |
Rabbit |
| Applications: |
IHC |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-APOL1 (179-398) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC-P 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
APOL1 |
| Gene ID: |
8542 |
| Uniprot ID: |
APOL1_HUMAN |
| Immunogen Region: |
179-398 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 179-398 of human APOL1 (NP_003652.2). |
| Immunogen Sequence: |
SGSLSISSGILTLVGMGLAP FTEGGSLVLLEPGMELGITA ALTGITSSTMDYGKKWWTQA QAHDLVIKSLDKLKEVREFL GENISNFLSLAGNTYQLTRG IGKDIRALRRARANLQSVPH ASASRPRVTEPISAESGEQV ERVNEPSILEMSRGVKLTDV APVSFFLVLDVVYLVYESKH LHEGAKSETAEELKKVAQEL EEKLNILNNNYKILQADQEL |
| Tissue Specificity | Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen. |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
| Function | May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. |
| Protein Name | Apolipoprotein L1Apolipoprotein LApo-LApolApolipoprotein L-IApol-I |
| Database Links | Reactome: R-HSA-2168880Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Apolipoprotein L1 antibodyAnti-Apolipoprotein L antibodyAnti-Apo-L antibodyAnti-Apol antibodyAnti-Apolipoprotein L-I antibodyAnti-Apol-I antibodyAnti-APOL1 antibodyAnti-APOL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
