Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-APOH (21-345) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
APOH |
Gene ID: |
350 |
Uniprot ID: |
APOH_HUMAN |
Immunogen Region: |
21-345 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 21-345 of human APOH (NP_000033.2). |
Immunogen Sequence: |
RTCPKPDDLPFSTVVPLKTF YEPGEEITYSCKPGYVSRGG MRKFICPLTGLWPINTLKCT PRVCPFAGILENGAVRYTTF EYPNTISFSCNTGFYLNGAD SAKCTEEGKWSPELPVCAPI ICPPPSIPTFATLRVYKPSA GNNSLYRDTAVFECLPQHAM FGNDTITCTTHGNWTKLPEC REVKCPFPSRPDNGFVNYPA KPTLYYKDKATFGCHDGYSL DGPEEIECTKLGNWSAMPS |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Post Translational Modifications | N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele. |
Function | Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. |
Protein Name | Beta-2-Glycoprotein 1Apc InhibitorActivated Protein C-Binding ProteinAnticardiolipin CofactorApolipoprotein HApo-HBeta-2-Glycoprotein IB2gpiBeta(2gpi |
Database Links | Reactome: R-HSA-114608 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Beta-2-Glycoprotein 1 antibodyAnti-Apc Inhibitor antibodyAnti-Activated Protein C-Binding Protein antibodyAnti-Anticardiolipin Cofactor antibodyAnti-Apolipoprotein H antibodyAnti-Apo-H antibodyAnti-Beta-2-Glycoprotein I antibodyAnti-B2gpi antibodyAnti-Beta(2gpi antibodyAnti-APOH antibodyAnti-B2G1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance