| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | APOB |
| Gene ID: | 338 |
| Uniprot ID: | APOB_HUMAN |
| Immunogen Region: | 28-463 |
| Immunogen Sequence: | NSLNIAGLSLDFSSKLDNIY SSDKFYKQTVNLQLQPYSLV TTLNSDLKYNALDLTNNGKL RLEPLKLHVAGNLKGAYQNN EIKHIYAISSAALSASYKAD TVAKVQGVEFSHRLNTDIAG LASAIDMSTNYNSDSLHFSN VFRSVMAPFTMTIDAHTNGN GKLALWGEHTGQLYSKFLLK AEPLAFTFSHDYKGSTSHHL VSRKSISAALEHKVSALLTP AEQTGTWKLKTQFNNNEYS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-330 of human ApoB (NP_000375.3). |
| Post Translational Modifications | Palmitoylated.structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle. |
| Function | Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. |
| Protein Name | Apolipoprotein B-100Apo B-100 Cleaved Into - Apolipoprotein B-48Apo B-48 |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-3000471Reactome: R-HSA-3000480Reactome: R-HSA-3000484Reactome: R-HSA-3000497Reactome: R-HSA-381426Reactome: R-HSA-432142Reactome: R-HSA-5686938Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-8866423Reactome: R-HSA-8957275Reactome: R-HSA-8963888Reactome: R-HSA-8963901Reactome: R-HSA-8964026Reactome: R-HSA-8964038Reactome: R-HSA-8964041Reactome: R-HSA-8964046Reactome: R-HSA-9707616Reactome: R-HSA-975634 |
| Cellular Localisation | CytoplasmSecretedLipid Droplet |
| Alternative Antibody Names | Anti-Apolipoprotein B-100 antibodyAnti-Apo B-100 Cleaved Into - Apolipoprotein B-48 antibodyAnti-Apo B-48 antibodyAnti-APOB antibody |
Information sourced from Uniprot.org
